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The metabolic actions of GLP-1 to control insulin, glucagon, glucose, and body weight are mediated by a single widely expressed GLP-1R (7, 8)
Vitamin B6 deficiency modulates cysteine synthesis, and it has been observed that supplementation with vit B6 was found to be beneficial because the enzymes CSE and CBS rely on pyridoxal 5-phosphate as a cofactor affects the flow through the reverse TSP
Tedi Totojani, then a Yale research fellow
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